45 (SE = 0.96) % and 17.45(1.05) % respectively among 1947 men and 2909
women. BTSA1 in vitro The odds ratios (ORs) were 1 (reference). 1.64(95% CI = 1.06, 2.54) and 2.34 (1.41, 3.87) respectively for men with lowest, middle and highest third of linoleic FA intake (p for trend = 0.001): the ORs were I (reference), 0.88 (0.56, 1.38) and 0.48 (0.25, 0.95) respectively for women with lowest, middle and highest third of oleic FA intake (p for trend = 0.0347). No association was observed from saturated FA. These estimates were adjusted for fish consumption at baseline and major physical diseases at follow-up. The authors concluded that increased intake of oleic FA was associated with reduced risk among women while increased intake of linoleic FA was associated with increased risk of SDM among men. (C) 2009 Published by Elsevier Inc.”
“Background Differences in systolic blood pressure (SBP) of 10 mm Hg or more or 15 mm Hg or more between arms have been associated with peripheral
vascular disease and attributed to subclavian stenosis. We investigated whether an association exists between this difference and central or peripheral vascular disease, and mortality.
Methods We searched Medline, Embase, Cumulative Index to Nursing and Allied Health Literature, Cochrane, and Medline In Process databases for studies published before July, 2011, showing differences in SBP between arms, with data for subclavian stenosis, peripheral vascular disease, cerebrovascular disease, cardiovascular disease, or survival. We Anlotinib cell line used random effects meta-analysis to combine estimates of the association between differences in SBP between arms and each outcome.
Findings We identified 28 eligible
studies for review, 20 of which were included in our meta-analyses. In five invasive studies using angiography, mean difference in SBP between arms was 36.9 mm Hg (95% CI 35.4-38.4) for proven subclavian stenosis (>50% occlusion), and a difference of 10 mm Hg or more was strongly associated with subclavian learn more stenosis (risk ratio [RR] 8.8, 95% CI 3.6-21.2). In non-invasive studies, pooled findings showed that a difference of 15 mm Hg or more was associated with peripheral vascular disease (nine cohorts; RR 2.5, 95% CI 1.6-3.8; sensitivity 15%, 9-23; specificity 96%, 94-98); pre-existing cerebrovascular disease (five cohorts; RR 1.6, 1.1-2.4; sensitivity 8%, 2-26; specificity 93%, 86-97); and increased cardio vascular mortality (four cohorts; hazard ratio [HR] 1.7, 95% CI 1.1-2.5) and all-cause mortality (HR 1.6, 1.1-2.3). A difference of 10 mm Hg or higher was associated with peripheral vascular disease (five studies; RR 2.4, 1.5-3.9; sensitivity 32%, 23-41; specificity 91%, 86-94).
Interpretation A difference in SBP of 10 mm Hg or more, or of 15 mm Hg or more, between arms might help to identify patients who need further vascular assessment. A difference of 15 mm Hg or more could be a useful indicator of risk of vascular disease and death.