To test for a neural representation of more qualitative coincidences instead of the correlation coefficient with estimated another GLM, similar to the main GLM except that the parametric modulators ρ and ζ were replaced by a binary parametric modulator with a coincidence value of sign(td1)∗sign(td2). To test for a relationship between behavior and neural model fit we compared R2 (explained variance) in the behavioral model with the R2 in the fMRI GLM. An R2 value for the behavioral model was calculated for every subject selleck compound by regressing trial-by-trial model predicted choice on subject’s actual choices. We calculated the R2 value for the fMRI regression as the proportion of

variance in BOLD that was explained by our interest regressors in relation to the

total variance (R2 = RSSreg/RSStot), where RSSreg equals the explained variance (variance of the predicted time course ypred = Xb, X = design matrix and b the regression coefficient) and RSStot is the variance of the bold signal after adjusting for block and nuisance effects. We also tested the influence of potential confounding variables on this relationship, namely the fitted learning rate and the average absolute amount of weight updating per trial, by calculating partial correlations. This analysis confirmed a significant correlation between behavioral and neural fit (rxy = 0.54, p = 0.04) after accounting for potential confounds. Cisplatin Furthermore, there was no relationship between these potential confounds and neural fit (ray = 0.12, p = 0.66; r|w|y = −0.14, p = 0.63). We performed posthoc an exploratory PPI analysis (Friston et al., 1997) to investigate changes in functional connectivity with right midinsula

at the time of outcome (when almost all task related activity was observed). The PPI term was Y the × P, with Y being the BOLD time courses in the insula region of interest analysis and P indicating the time during the outcome screen. We then entered the seed region BOLD Y, the psychological variable P, and the PPI interaction term into a new GLM. Findings from this analysis are reported in Figure S4. This study was supported by a Wellcome Trust Program Grant and Max Planck Award. “
“Periodised training programs of elite athletes are most often comprised of a balance between phases of high training loads and active recovery or rest.1 and 2 Establishing the right balance between these aspects for athletes, in particular understanding when to rest, can often be quite difficult to achieve.3 Despite the potential value and importance of monitoring an athlete’s state of recovery, there are few adequate or convenient tools for monitoring daily recovery.4 Though most training induced adaptations occur while at rest, recovery is one of the most under researched components of the stress–recovery cycle.