These corresponded to a cubosome formulation made from 100 mg of monoolein, 107 mg of polymer, and 2 mg with average diameter of 104.7 nm and an encapsulation efficiency of 6.9%. The Box-Behnken design proved to be Vorinostat purchase a useful tool to optimize the particle size of these drug-loaded cubosomes. For encapsulation efficiency (Y (2)), further studies are needed to identify appropriate regression model.”
“In this study we describe a simple method to fabricate microarrays of polystyrene microbeads (PS-mu beads) on Thermanox coverslip surfaces using laser induced forward transfer (LIFT). A triazene polymer layer which
acts as a dynamic release layer and propels the closely packed microspheres on the receiving substrate was used for this approach. The deposited features were characterized by optical microscopy, scanning electron microscopy, atomic force microscopy, GF120918 purchase and Raman spectroscopy. Ultrasonication was used to test the adherence of the transferred beads. In addition, the laser ejection of the PS-mu beads pixels was investigated by time resolved shadowgraphy. It was found that stable PS-mu beads micropatterns without any specific immobilization process could be realized by LIFT. These results highlight the increasing role of LIFT in the development of biomaterials, drug delivery, and tissue engineering. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3466746]“
“Liquid
gel polymer electrolyte (LGPE) based on chitosan, ammonium nitrate, and acetic acid with a ratio of 1.9 : 0.17 : 96.3 wt % gives the highest conductivity MK-8931 price of (1.46 +/- 0.07) 10(-1) S cm(-1) at room temperature. This optimized composition of electrolyte is then used in proton batteries with the configuration of Zn + ZnSO4 center dot H2O/LGPE/MnO2. The open circuit voltage of battery is 1.41 V during 48 h of storage. The battery obtained a discharge capacity of 27.90 mA h(-1) upon discharge at 1.0 mA current. The maximum power density for the battery is 3.67 mW cm(-2). (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 118: 1240-1243, 2010″
“The purpose of this study is to investigate
the combined influence of process parameters (independent variables) such as homogenization speed (X (1)), duration (X (2)), and temperature (X (3)) during the preparation of dacarbazine-loaded cubosomes. Box-Behnken design was used to rationalize the influence of these three factors on two responses, namely particle size (Y (1)) and encapsulation efficiency (Y (2)). Independent and dependent variables were analyzed with multiple regressions to establish a full-model second-order polynomial equation. F value was calculated to confirm the omission of insignificant parameters or interactions of parameters from the analysis to derive a reduced-model polynomial equation to predict the Y (1) and Y (2) of dacarbazine-loaded cubosomes. Pareto charts were also obtained to show the effects of X (1), X (2), and X (3) on Y (1) and Y (2).