“
“The objective of this study was to determine the possible use of heifer pregnancy at 16 mo as a selection criterion and its possible genetic associations with hip height,

yearling weight, and visual scores of conformation, finishing, and muscling. The data set contained records of 56,458 Nelore yearlings for the traits described above. Covariance components were estimated by bivariate animal models assuming a linear model for hip height, yearling weight and conformation, and finishing and muscling scores, and a nonlinear (threshold) model DAPT ic50 for heifer pregnancy. Variance components were estimated using Bayesian inference. Flat distributions were used for all (co) variance components and genetic correlations. The first 5,000 rounds were considered as the burn-in period and discarded. The heritability estimate of heifer pregnancy indicates that the trait can be used as a selection criterion. Long-term selection for heifer pregnancy will result in a reduction of animal height. Z-VAD-FMK mechanism of action However, selection for increasing yearling weight should be possible in this population of Nelore cattle without having major effects on fertility. Selection for increasing visual scores of conformation, finishing, and muscling will result

in small or no response in heifer pregnancy at 16 mo.”
“A novel green route to synthesize sodium benzoate from the one-pot oxidation of benzyl alcohol using air as the oxidant and AuAg/TiO2 as the catalyst under solvent-free conditions is presented. This process proceeds with advantages from the viewpoint of green chemistry due to non-toxic reagents, no waste emission and high recyclability of catalysts, which can retain high catalytic activity (yield >75%) even after 6 runs.”
“Selenocystine (CysSeSeCys), a diselenide aminoacid

exhibiting glutathione peroxidase-like activity and selective antitumor effects, was examined for in vivo antigenotoxic and antioxidant see more activity in Swiss albino mice after exposure to a sublethal dose (5 Gy) of gamma-radiation. For this, CysSeSeCys was administered intraperitoneally (i.p.) to mice at a dosage of 0.5 mg/kg body weight for 5 consecutive days prior to whole-body gamma-irradiation. When examined in the hepatic tissue, CysSeSeCys administration reduced the DNA damage at 30 min after radiation exposure by increasing the rate of DNA repair. Since antigenotoxic agents could alter the expression of genes involved in cell cycle arrest and DNA repair, the transcriptional changes in p53, p21 and GADD45 alpha were monitored in the hepatic tissue by real-time PCR. The results show that CysSeSeCys alone causes moderate induction of these three genes. However, CysSeSeCys pretreatment resulted in a suppression of radiation-induced enhancement of p21 and GADD45 alpha expression, but did not affect p53 expression.