Nucleic Acids Res 2002,30(4):e15.PubMedCentralPubMedCrossRef 34. marray – a Bioconductor package for exploratory analysis for two-color spotted microarray data. http://www.bioconductor.org/packages/release/bioc/html/marray.html 35. Reiner A, Yekutieli D, Benjamini Y: Identifying differentially expressed
genes using false discovery rate controlling procedures. Bioinformatics click here 2003,19(3):368–375.PubMedCrossRef 36. Delmar P, Robin S, Daudin JJ: VarMixt: efficient variance modelling for the differential analysis of replicated gene expression data. Bioinformatics 2005,21(4):502–508.PubMedCrossRef 37. The Sanger Institute Streptomyces coelicolor protein classification scheme ftp://ftp.sanger.ac.uk/pub/S_coelicolor/classwise.txt
38. Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2 –ΔΔC T method. Methods 2001,25(4):402–408.PubMedCrossRef 39. Hiard S, Maree R, Colson S, Hoskisson PA, Titgemeyer F, van Wezel GP, Joris B, Wehenkel L, Rigali S: PREDetector: a new tool to identify regulatory elements in bacterial genomes. Biochem Biophys Res Commun 2007,357(4):861–864.PubMedCrossRef 40. Derre I, Rapoport G, Msadek T: CtsR, a novel Selleckchem MAPK inhibitor regulator of stress and Selleckchem VS-4718 heat shock response, controls clp and molecular chaperone gene expression in Gram-positive bacteria. Mol Microbiol 1999,31(1):117–131.PubMedCrossRef 41. Jayapal KP, Lian W, Glod F, Sherman DH, Hu WS: Comparative genomic hybridizations reveal absence of large Streptomyces coelicolor genomic islands in Streptomyces lividans . BMC Genomics 2007, 8:229.PubMedCentralPubMedCrossRef 42. Hesketh A, Bucca G, Laing E, Flett F, Hotchkiss G, Smith CP, Chater KF: New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor , revealed by combined proteomic and
transcriptomic analysis of liquid cultures. BMC Genomics 2007, 8:261.PubMedCentralPubMedCrossRef 43. Lautru S, Deeth RJ, Bailey LM, Challis GL: Discovery of a new peptide natural product by Streptomyces coelicolor genome mining. Nat Chem Biol 2005,1(5):265–269.PubMedCrossRef 44. Koebsch I, Overbeck Liothyronine Sodium J, Piepmeyer S, Meschke H, Schrempf H: A molecular key for building hyphae aggregates: the role of the newly identified Streptomyces protein HyaS. Microb Biotechnol 2009,2(3):343–360.PubMedCentralPubMedCrossRef 45. Chun YJ, Shimada T, Sanchez-Ponce R, Martin MV, Lei L, Zhao B, Kelly SL, Waterman MR, Lamb DC, Guengerich FP: Electron transport pathway for a Streptomyces cytochrome P450: cytochrome P450 105D5-catalyzed fatty acid hydroxylation in Streptomyces coelicolor A3(2). J Biol Chem 2007,282(24):17486–17500.PubMedCrossRef 46. Li WC, Wu J, Tao WX, Zhao CH, Wang YM, He XY, Chandra G, Zhou XF, Deng ZX, Chater KF, Tao MF: A genetic and bioinformatic analysis of Streptomyces coelicolor genes containing TTA codons, possible targets for regulation by a developmentally significant tRNA.