Int J Oncol 2005, 27: 669–679. 7. Bierer S, Herrmann E, Kopke T, Neumann J, Eltze E, Hertle L, Wulfing C: Lymphangiogenesis
in kidney cancer: expression of VEGF-C, VEGF-D and VEGFR-3 in clear cell and papillary renal cell carcinoma. Oncol Rep 2008, 20: 721–725.PubMed 8. Inoue A, Moriya H, Katada N, Tanabe S, Kobayashi N, Watanabe M, Okayasu I, Ohbu M: Intratumoral lymphangiogenesis of esophageal squamous Angiogenesis inhibitor cell carcinoma and relationship with regulatory factors and prognosis. Pathol Int 2008, 58: 611–619.CrossRefPubMed 9. Zhang SQ, Yu H, Zhang LL: Clinical implications of increased lymph vessel density in the lymphatic metastasis of early-stage invasive cervical carcinoma: a clinical immunohistochemical method study. BMC Cancer 2009, 9: 64.CrossRefPubMed 10. Krishnan J, Kirkin V, Steffen A, Hegen M, Weih D, Tomarev S, Wilting J, selleck products Sleeman JP: Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats. Cancer Res 2003, 63: 713–722.PubMed 11. Nathanson
SD: Insights into the mechanisms of lymph node metastasis. Cancer 2003, 98: 413–423.CrossRefPubMed 12. Neuchrist C, Erovic BM, Handisurya A, Fischer MB, Steiner GE, Hollemann D, Gedlicka C, Saaristo A, Burian M: Vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 expression in squamous cell carcinomas of the head and neck. Head Neck
2003, 25: 464–474.CrossRefPubMed 13. Wu W, Shu X, Hovsepyan H, Selleckchem Rabusertib Mosteller RD, Broek D: VEGF receptor expression and signaling in human bladder tumors. Oncogene 2003, 22: 3361–3370.CrossRefPubMed 14. Byzova TV, Goldman CK, Pampori N, Thomas KA, Bett A, Shattil SJ, Plow EF: A mechanism for modulation of cellular responses to VEGF: activation of much the integrins. Mol Cell 2000, 6: 851–860.PubMed 15. Su JL, Yang PC, Shih JY, Yang CY, Wei LH, Hsieh CY, Chou CH, Jeng YM, Wang MY, Chang KJ, Hung MC, Kuo ML: The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells. Cancer Cell 2006, 9: 209–223.CrossRefPubMed 16. Van Trappen PO, Steele D, Lowe DG, Baithun S, Beasley N, Thiele W, Weich H, Krishnan J, Shepherd JH, Pepper MS, Jackson DG, Sleeman JP, Jacobs IJ: Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D, and their receptor VEGFR-3, during different stages of cervical carcinogenesis. J Pathol 2003, 201: 544–554.CrossRefPubMed 17. Masood R, Kundra A, Zhu S, Xia G, Scalia P, Smith DL, Gill PS: Malignant mesothelioma growth inhibition by agents that target the VEGF and VEGF-C autocrine loops. Int J Cancer 2003, 104: 603–610.CrossRefPubMed 18. Timoshenko AV, Rastogi S, Lala PK: Migration-promoting role of VEGF-C and VEGF-C binding receptors in human breast cancer cells.