9 mol%. Analysis of the 16S rRNA gene sequence of strain CL-ES53(T) revealed that it was a member of the genus Salinisphaera and most closely related to Salinisphaera shabanensis E1L3A(T) (96.9% sequence similarity) and Salinisphaera hydrothermalis EPR70(T) (93.8%). Phylogenetic analyses based on the 16S rRNA gene sequence showed that strain CL-ES53(T) formed a robust cluster with S. shabanensis E1L3A(T). Although the 16S rRNA gene sequence similarity between strain CL-ES53(T) and S. shabanensis E1L3A(T) was rather high (96.9%),

DNA-DNA relatedness between these strains was 12%, suggesting that they represent SYN-117 genomically distinct species. Strain CL-ES53(T) was differentiated from S. shabanensis E1L3A(T) and S. hydrothermalis EPR70(T) on the basis of optimum temperature for growth and certain phenotypic characteristics. The phylogenetic analysis and physiological and chemotaxonomic data show that strain CL-ES53(T) should be classified in the genus Salinisphaera within a novel species, for which the name Salinisphaera dokdonensis sp. nov. is proposed. The type strain is CL-ES53(T) (= KCCM

90064(T) = DSM 19549(T)).”
“The incidence of postoperative cognitive dysfunction (POCD) depends on the test battery and calculation method used. The measurements may be performed with a paper and pencil test battery or with a computerized test battery. The objective of this study was to measure the

incidence and congruence of POCD by comparing a computerized test Selleckchem GSK3235025 battery with a paper and pencil test battery in the same patient population.\n\nIn total, 67 patients were included: 30 consecutive in-patients undergoing surgery under general anesthesia and 37 non-surgical out-patients as control. Patients were tested with a paper and pencil test battery and a computerized test battery on inclusion in the study and 7 days later. Both test batteries covered the cognitive domains: visual attention, visual learning, memory, and speed of processing.\n\nThe computerized test battery classified 10.0% (95% CI 3.5-25.6%) of the patients as suffering from POCD whereas the paper and INCB028050 concentration pencil test battery classified 30.0% (95% CI 16.7-47.9%) as suffering (95% CI for difference 3.9-36.5%, P = 0.03). The inter-rater reliability between both test batteries showed moderate agreement (Cohen’s kappa of 0.41). All patients identified by use of the computerized test battery were also identified with the paper and pencil test battery. The paper and pencil test battery identified 6 additional cases.\n\nIn our study we demonstrated that the incidence of POCD measured with computerized test battery and paper and pencil test battery showed moderate inter-rater reliability. Use of neuropsychological test batteries theoretically covering the same cognitive domains does not automatically lead to the same classification of POCD.